Introduction: Multidrug Resistants Tuberculosis (MDRTB) is the biggest problem of preventive and elimination Tuberculosis (TB) Programmed globally, including in Indonesia. It is more difficult when new Mycobacterium tuberculosis strains are resistant to Anti Tuberculosis Therapy (ATT). Objective: This study aims to describe knowledge about MDR-TB on commuter train users in
2020 and its risk factors. Method: This research is an observational study that uses a Cross-sectional design study. The sample is 100 commuter train users who are≥18 years old and use commuter train routines. The analysis was done in the Chi-square test. Results: The result is 55%, or 55 participants have insufficient knowledge about MDR-TB which the question that has less correct answers is the meaning of MDR-TB (31%), diagnosis method of MDR-TB (33%), and the causes of MDR-TB (36%). It also showed there is the relation of profession status (p-value: 0.019) and educational status (p-value: 0.044) with MDR-TB knowledge, and there is no relation of age (p-value: 0.0227) and gender (p-value: 0.096) with MDR-TB knowledge. So, more than half of the participants have insufficient knowledge of MDR-TB, and the risk factors of MDR-TB knowledge are professional status and educational status.
Recommendation: To increase knowledge, it can do socialization of MDR-TB using short video and poster in each railway coach.